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JFK’s Granddaughter Tatiana Schlossberg Courageously Shares Terminal Leukemia Battle in Heartbreaking Public Revelation

November 24, 2025
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In a moment of profound courage and vulnerability, Tatiana Schlossberg, granddaughter of the late President John F. Kennedy, has publicly disclosed her battle with terminal cancer through a deeply moving essay published in The New Yorker. The 35-year-old journalist and author revealed that medical professionals have given her less than a year to live.

Schlossberg’s devastating diagnosis came at what should have been one of life’s most joyful moments—shortly after welcoming her daughter in May 2024. Medical tests confirmed she was suffering from acute myeloid leukemia, a particularly aggressive form of blood cancer that attacks the bone marrow and blood.

The diagnosis became even more challenging when doctors identified a rare genetic abnormality called Inversion 3, a mutation that significantly complicates treatment options and is associated with poor patient outcomes. This genetic factor has made Schlossberg’s battle against the disease particularly difficult, despite the advanced medical care she has received.

Over the past year and a half, the granddaughter of America’s 35th president has endured an exhausting regimen of treatments in her fight against the disease. Her medical journey has included multiple rounds of intensive chemotherapy, each taking a tremendous physical and emotional toll as she battles to spend more time with her young daughter.

Schlossberg’s decision to share her story publicly demonstrates the same sense of public service that has long characterized the Kennedy family legacy. By speaking openly about her terminal diagnosis, she joins a tradition of Kennedy family members who have used their platform to bring awareness to important causes and human struggles.

The journalist, who has built a distinguished career as an environmental reporter and author, chose The New Yorker as the venue for her deeply personal revelation. Her essay not only shares the clinical details of her condition but also provides insight into the emotional journey of facing terminal illness while trying to be present for her infant daughter.

Acute myeloid leukemia affects approximately 20,000 Americans each year, making it a relatively rare form of cancer. The disease progresses rapidly, attacking the blood and bone marrow, and requires immediate and aggressive treatment. The presence of the Inversion 3 genetic abnormality in Schlossberg’s case makes her situation particularly challenging, as this mutation is found in only a small percentage of AML patients and is known for its resistance to standard treatments.

As the daughter of Caroline Kennedy, former U.S. Ambassador to Japan, and granddaughter of President Kennedy and Jacqueline Kennedy Onassis, Tatiana Schlossberg has lived her life largely out of the public spotlight, focusing on her career in journalism and environmental advocacy. Her decision to share this most personal battle represents a significant departure from her typically private approach to public attention.

The Kennedy family has faced numerous tragedies throughout the decades, from political assassinations to accidental deaths, earning them the somber nickname of America’s “cursed” political dynasty. Schlossberg’s cancer battle adds another chapter to the family’s long history of confronting adversity with grace and dignity.

Her brave disclosure serves not only as a personal testimony but also as a potential source of comfort and inspiration for other families facing similar battles with terminal illness. By sharing her story, Schlossberg continues the Kennedy tradition of public service, this time through the deeply personal act of bearing witness to one of life’s most difficult journeys.

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